( CNN) The job of White House chief of staff is close to impossible at the best of days, but President Donald Trump's new West Wing enforcer faces an even tougher mission — one that may eventually evolve into an effort to save his presidency itself.

The long-expected departure of the current incumbent, John Kelly, announced by Trump on Saturday, comes at a time of instability and crisis that is remarkable even for this riotous administration where turbulence is the rule.

Nick Ayers, a rising political starring in the GOP — who had long been considered Kelly's likely replacing after serving as Vice President Mike Pence's chief of staff — announced Sunday he would not take the position after talks with Trump.